A Nasal Vaccine Against Tau Tangles

One of the hallmarks of Alzheimer’s disease (AD) is the accumulation of “tau tangles”. Tau is a protein associated with the axons of nerve cells and plays a critical role in shuttling nutrients and other essential molecules to brain cells. In Alzheimer’s patients, tau fibrils aggregate into knotted masses, resulting in nerve cell death and cognitive decline. Memory loss and personality changes are among some of the earliest…