CRISPR Pumps the Brakes on the Immune System to Support Gene Therapies

The ability to edit the human genome using CRISPR has been heralded as a revolution in medicine. However, one of the biggest challenges facing gene therapies is getting this molecule gene-editing machinery into cells. Among the most common delivery approaches is the use of viruses such as the adeno-associated virus (AAV), which shuttle CRISPR into the nuclei of cells…