Gene Silencing Therapy Stops the Itch of Psoriasis

A team of Harvard researchers has identified a promising new approach for treating psoriasis — a topical lotion containing nucleic acids that transiently disrupt inflammatory gene activity. This ionic liquid (IL) contains small interfering RNA, or siRNA, which when used in an experimental mouse model of the itchy skin disease, drastically reduced the levels of inflammation-causing cytokines and soothed…