Prime editor: the rise of a new gene-editing superhero

Prime Editing Superhero © Tara Fernandez

In a dark corner of the nucleus, a mutation lurks, up to no good. It stealthily swaps a DNA base — an A to a T — gleefully awaiting the catastrophic consequences on the encoded protein.

A brave CRISPR molecule enters the nucleus and armed with its razor sharp enzyme, Cas9, is determined to rid this genome of unwanted errors. Its other secret weapon, guide RNA, acts like…



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River D'Almeida, Ph.D

Follow me for bite-sized stories on the latest discoveries and innovations in biomedical research.