Prime editor: the rise of a new gene-editing superhero

Prime Editing Superhero © Tara Fernandez

In a dark corner of the nucleus, a mutation lurks, up to no good. It stealthily swaps a DNA base — an A to a T — gleefully awaiting the catastrophic consequences on the encoded protein.

A brave CRISPR molecule enters the nucleus and armed with its razor sharp enzyme, Cas9, is determined to rid this genome of unwanted errors. Its other secret weapon, guide RNA, acts like…

--

--

Get the Medium app

A button that says 'Download on the App Store', and if clicked it will lead you to the iOS App store
A button that says 'Get it on, Google Play', and if clicked it will lead you to the Google Play store
River D'Almeida, Ph.D

Follow me for bite-sized stories on the latest discoveries and innovations in biomedical research.